Suggest an update Name* Categories* State* Locality* ZIP* Street address* Phone* Website* Company description* Visit the hotel Comfort Inn, which is in the state Virginia (VA), city Wytheville. Our hotel can be found at 315 Holston Rd, Wytheville, VA 24382-4450. Great deals on best and cheap hotels. Your comments* (not for publishing) * — Required information Comfort Inn/315 Holston Rd - Wytheville - Virginia (VA) ← View details 315 Holston Rd, Wytheville, VA 24382-4450, Wytheville, Virginia (VA) 00 1849-8551513